2,714 research outputs found

    Lorentzian symmetry predicts universality beyond scaling laws

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    Rhythms of Locomotion Expressed by Limulus polyphemus, the American Horseshoe Crab: I. Synchronization by Artificial Tides

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    Limulus polyphemus, the American horseshoe crab, has an endogenous clock that drives circatidal rhythms of locomotor activity. In this study, we examined the ability of artificial tides to entrain the locomotor rhythms of Limulus in the laboratory. In experiments one and two, the activity of 16 individuals of L. polyphemus was monitored with activity boxes and “running wheels.” When the crabs were exposed to artificial tides created by changes in water depth, circatidal rhythms were observed in animals exposed to 12.4-h “tidal” cycles of either water depth changes (8 of 8 animals) or inundation (7 of 8 animals). In experiment three, an additional 8 animals were exposed to water depth changes under cyclic conditions of light and dark and then monitored for 10 days with no imposed artificial tides. Most animals (5) clearly synchronized their activity to the imposed artificial tidal cycles, and 3 of these animals showed clear evidence of entrainment after the artificial tides were terminated. Overall, these results demonstrate that the endogenous tidal clock that influences locomotion in Limulus can be entrained by imposed artificial tides. In the laboratory, these tidal cues override the influence of light/dark cycles. In their natural habitat, where both tidal and photoperiod inputs are typically always present, their activity rhythms are likely to be much more complex

    Fluid flow and heat transfer in a dual-wet micro heat pipe

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    Micro heat pipes have been used to cool micro electronic devices, but their heat transfer coefficients are low compared with those of conventional heat pipes. In this work, a dual-wet pipe is proposed as a model to study heat transfer in micro heat pipes. The dual-wet pipe has a long and narrow cavity of rectangular cross-section. The bottom-half of the horizontal pipe is made of a wetting material, and the top-half of a non-wetting material. A wetting liquid fills the bottom half of the cavity, while its vapour fills the rest. This configuration ensures that the liquid–vapour interface is pinned at the contact line. As one end of the pipe is heated, the liquid evaporates and increases the vapour pressure. The higher pressure drives the vapour to the cold end where the vapour condenses and releases the latent heat. The condensate moves along the bottom half of the pipe back to the hot end to complete the cycle. We solve the steady-flow problem assuming a small imposed temperature difference between the two ends of the pipe. This leads to skew-symmetric fluid flow and temperature distribution along the pipe so that we only need to focus on the evaporative half of the pipe. Since the pipe is slender, the axial flow gradients are much smaller than the cross-stream gradients. Thus, we can treat the evaporative flow in a cross-sectional plane as two-dimensional. This evaporative motion is governed by two dimensionless parameters: an evaporation number E defined as the ratio of the evaporative heat flux at the interface to the conductive heat flux in the liquid, and a Marangoni number M. The motion is solved in the limit E→∞ and M→∞. It is found that evaporation occurs mainly near the contact line in a small region of size E−1W, where W is the half-width of the pipe. The non-dimensional evaporation rate Q* ~ E−1 ln E as determined by matched asymptotic expansions. We use this result to derive analytical solutions for the temperature distribution Tp and vapour and liquid flows along the pipe. The solutions depend on three dimensionless parameters: the heat-pipe number H, which is the ratio of heat transfer by vapour flow to that by conduction in the pipe wall and liquid, the ratio R of viscous resistance of vapour flow to interfacial evaporation resistance, and the aspect ratio S. If HRxs226B1, a thermal boundary layer appears near the pipe end, the width of which scales as (HR)−1/2L, where L is the half-length of the pipe. A similar boundary layer exists at the cold end. Outside the boundary layers, Tp varies linearly with a gradual slope. Thus, these regions correspond to the evaporative, adiabatic and condensing regions commonly observed in conventional heat pipes. This is the first time that the distinct regions have been captured by a single solution, without prior assumptions of their existence. If HR ~ 1 or less, then Tp is linear almost everywhere. This is the case found in most micro-heat-pipe experiments. Our analysis of the dual-wet pipe provides an explanation for the comparatively low effective thermal conductivity in micro heat pipes, and points to ways of improving their heat transfer capabilities

    Symptoms of Meares-Irlen/visual stress syndrome in subjects diagnosed with chronic fatigue syndrome

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    Several diagnostic symptoms of the visual-processing deficit Meares-Irlen/Visual Stress Syndrome are remarkably similar to symptom manifestations reported by individuals with chronic fatigue syndrome (CFS). We surveyed the specific incidences of nine widely-recognised symptoms of visual stress (VS) in a group of subjects (n = 20) previously diagnosed with CFS. The presence of each symptom of VS in the CFS group was compared to its respective presence in both an age and sex matched healthy comparison group (n = 46), and an age and sex matched group comprised of individuals (n = 14) diagnosed with VS. Results showed the frequencies of all nine VS symptoms in the CFS-diagnosed group to be significantly higher (p = .032 – p < .0005) than in the comparison group, with only two symptoms being statistically less frequent in the CFS group than in the VS-diagnosed group. The average number of VS symptoms reported by the CFS group was also significantly higher than the comparison group, yet not significantly different from the VS group. Thus, the occurrence of VS symptoms in subjects diagnosed with CFS appears to be far greater than previously reported, which in turn may indicate the interplay of some yet to be identified underlying factor(s) common to both conditions

    Analytic structure of radiation boundary kernels for blackhole perturbations

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    Exact outer boundary conditions for gravitational perturbations of the Schwarzschild metric feature integral convolution between a time-domain boundary kernel and each radiative mode of the perturbation. For both axial (Regge-Wheeler) and polar (Zerilli) perturbations, we study the Laplace transform of such kernels as an analytic function of (dimensionless) Laplace frequency. We present numerical evidence indicating that each such frequency-domain boundary kernel admits a "sum-of-poles" representation. Our work has been inspired by Alpert, Greengard, and Hagstrom's analysis of nonreflecting boundary conditions for the ordinary scalar wave equation.Comment: revtex4, 14 pages, 12 figures, 3 table

    Navier-Stokes-Fourier system with phase transitions

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    We consider the Navier-Stokes-Fourier (NSF ) system for a class of compressible fluids that exhibit a gas-liquid phase transition at low temperatures. For the initial-boundary value problem corresponding to thermally insulated end-points that are held at a constant pressure, weestablish the existence and uniqueness of temporally global classical solutions. A novel feature of the analysis presented here is the derivation of uniform point-wise apriori estimates on the specific volume, which refines the non-uniform estimates framework developed in [W1]

    Resting state correlates of subdimensions of anxious affect

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    Resting state fMRI may help identify markers of risk for affective disorder. Given the comorbidity of anxiety and depressive disorders and the heterogeneity of these disorders as defined by DSM, an important challenge is to identify alterations in resting state brain connectivity uniquely associated with distinct profiles of negative affect. The current study aimed to address this by identifying differences in brain connectivity specifically linked to cognitive and physiological profiles of anxiety, controlling for depressed affect. We adopted a two-stage multivariate approach. Hierarchical clustering was used to independently identify dimensions of negative affective style and resting state brain networks. Combining the clustering results, we examined individual differences in resting state connectivity uniquely associated with subdimensions of anxious affect, controlling for depressed affect. Physiological and cognitive subdimensions of anxious affect were identified. Physiological anxiety was associated with widespread alterations in insula connectivity, including decreased connectivity between insula subregions and between the insula and other medial frontal and subcortical networks. This is consistent with the insula facilitating communication between medial frontal and subcortical regions to enable control of physiological affective states. Meanwhile, increased connectivity within a frontoparietal-posterior cingulate cortex-precunous network was specifically associated with cognitive anxiety, potentially reflecting increased spontaneous negative cognition (e.g., worry). These findings suggest that physiological and cognitive anxiety comprise subdimensions of anxiety-related affect and reveal associated alterations in brain connectivity

    The prevalence of symptoms of scotopic sensitivity/Meares-Irlen syndrome in subjects diagnosed with ADHD: Does misdiagnosis play a significant role?

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    Previous investigations of the visual-perception disorder scotopic sensitivity syndrome (SSS), also known as Meares-Irlen syndrome, have identified several clinical features of symptom manifestation which are strikingly similar to those found in attention deficit/ hyperactivity disorder (ADHD). We surveyed the incidences of nine widely-recognised symptoms of SSS in individuals (n = 76), of whom one sub-group (n = 12) was comprised of subjects diagnosed with ADHD by qualified healthcare providers. The prevalence of each SSS symptom in the ADHD sub-group was compared to a second sub-group of diagnosed SSS individuals (n = 18), and also to a group of appropriately matched controls (n = 46). The data showed a remarkable lack of significant variations between the ADHD-diagnosed and SSS-diagnosed groups. In contrast, highly significant variations between the ADHD-diagnosed and control groups were clearly evident. The degree of symptom overlap between the ADHD and SSS disorders may be far stronger than previously reported and it is likely that many individuals with SSS may be misdiagnosed with ADHD
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